Misoprostol, sold under the brandname Cytotec among others, is a medication used to prevent and treat stomach ulcers, start labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus. Misoprostol is used for the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol, but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy. It causes uterine contractions and the ripening (effacement or thinning) of the cervix. Medical abortion has the advantage of being less invasive, and more autonomous, self-directed, and discreet. Cytotec Tablet is used for Pregnancy termination, Legal abortion, Blood loss, Gastric ulcers, Cervical ripening before surgical pregnancy termination, Nsaid associated gastrointestinal injury, Benign gastric ulcer, Duodenal ulcer and other conditions. Cytotec Tablet may also be used for purposes not listed in this medication guide. The following is a list of possible side-effects that may occur from all constituting ingredients of Cytotec Tablet. These side-effects are possible, but do not always occur. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. Before using Cytotec Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Tell your doctor if your condition persists or worsens. If you use other drugs or over the counter products at the same time, the effects of Cytotec Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly.
Cytotec ® misoprostol tablets warnings cytotec misoprostol administration to women who are pregnant can cause abortion, premature birth, or birth Each CYTOTEC Tablet contains 200 mcg misoprostol. PHARMACOLOGICAL CLASSIFICATION A 11.10 - Medicines acting on the gastrointestinal tract.