Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Mechanism of resistance to chloroquine Plaquenil side effects cough In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. I have been on plaquenil for many a year, and it has not affected my weight at all. If you go to or rxlist.com, neither of them list weight gain as a side effect, while they both list "nausea, vomiting, stomach pain; loss of appetite, weight loss" as side effects. Find information about common, infrequent and rare side effects of Plaquenil Oral. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Will plaquenil cause weight gain Does Plaquenil Cause Weight Gain - Ironstone Vineyards, Weight gain while on Plaquenil? lupus Hydroxychloroquine 12.5mgIs plaquenil toxic to the liverChloroquine chikungunyaNosebleed plaquenilRheumatoid arthritis choosing initial treatment plaquenil vs enbrel Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid.. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Oral Route Description and Brand.. Oct 12, 2016 Which Drugs Cause Weight Gain, Loss in RA? by U. S. Medicine Oct 12, 2016. On average, compared to methotrexate-treated patients, prednisone-treated patients had significantly more weight gain, while leflunomide-treated patients demonstrated weight loss. In multivariable models, more weight loss and a greater risk of weight loss odds. Re Plaquenil and weight gain? Reply #7 on May 19, 2011, AM Thyroid issues, either being hyper or hypo both which are fairly common with SjS--especially being hypo can and typically do cause weight gain. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.