Hydroxychloroquine-induced pigmentation

Discussion in 'Canada Pharmacy' started by NVP, 18-Mar-2020.

  1. semsserv User

    Hydroxychloroquine-induced pigmentation


    In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent.

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    Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Blue–grey pigmentation of the skin affects up to 25% of patients taking hydroxychloroquine, especially where there has been bruising. Transverse pigmented nail bands and mucosal pigmentation have also been reported. Rashes may occur in up to 10% of patients, most commonly morbilliform or psoriasiform. IMPORTANCE Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising.

    Download PDF Many systemic medications may cause retinal toxicity. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended.

    Hydroxychloroquine-induced pigmentation

    Drug-associated hyperpigmentation of the oral mucosa report of four., Hydroxychloroquine DermNet NZ

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  6. On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful.

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    We report two cases of hydroxychloroquine‐induced hyperpigmentation presenting in a 50‐year‐old Caucasian female case 1 and a 78‐year‐old female case 2, both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4–5 years. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, The previous ophthalmological examination had been made 3 years before and there was no sign of retinal involvement. A skin biopsy was performed and showed pigment deposition in superficial dermis with haemosiderin characteristics—Perls Prussian staining was positive for iron and Fontana-Masson staining was negative for melanin.

     
  7. Crocodylus Moderator

    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil side effects - kidney problems? - Symptoms - Life. Hydroxychloroquine Plaquenil
     
  8. Mitroffan Guest

    Conditions Plaquenil-related Eye Problems Eugene Eye Care Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects.

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