Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and tlr signaling Wallace 1989 chloroquine Does plaquenil show up in a drug test This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil ® hydroxychloroquine sulfate is a prescription anti-malarial medicine. It is possible to take too much of this medication. The specific effects of a Plaquenil overdose can be quite dangerous and will vary depending on a number of factors, including the Plaquenil dosage and whether it was taken with any other medications or substances. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine overdose side effects Symptoms and Possible Side Effects of Hydroxychloroquine., Plaquenil Oral Uses, Side Effects, Interactions. Plaquenil oral mucosaChloroquine skin pigmentationIs chloroquine safe in first trimester of pregnancyCan plaquenil cause hair thinning Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Plaquenil Overdose - Antibiotics Home Page. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD used for rheumatoid arthritis and lupus. Learn how long it takes, risks and side-effects. Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs.