While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. Quinacrine and hydroxychloroquine lupus panniculitis Prozac and plaquenil Benefits of plaquenil for sjogren& 39 How to manage inflammation after coming off hydroxychloroquine Reviews and ratings for plaquenil when used in the treatment of rheumatoid arthritis. I rated it an 8 because I do not feel sick after taking it and it does seem to work. "This medication did wonders for my soreness and pain from Rheumatoid Arthritis but if someone would have told me I would have devastating and. Mar 24, 2011 no methotrexate doesn't always mean your hair will fall out or thin but some of the side effects are scary, but before you an progress onto other meds methotrexate is mandatory. for me methotreaxte and plaquenil does't work and i' intonate of sulfa so i am started embrel which states you have to have tried 2 of 3 meds and methotrexate is 1 of them. Hydroxychloroquine doesn’t work immediately. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first; even when your symptoms improve to help keep the disease under control. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. What if plaquenil doesn t work Lupus Board Index how does plaquenil work, What next if plaquenil doesn't work? - Flu shot and hydroxychloroquineNormal dosage of plaquenilHow long to see effects of plaquenil User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Plaquenil User Reviews for Rheumatoid Arthritis at. Hydroxychloroquine Side-effects, uses, time to work. If Your RA Biologic Doesn’t Help Enough What Next?. Oct 22, 2009 It's still not terribly long since you started Plaquenil. Many of us found it a slow process and yes there were times we thought we were winning and then another flare came along. Ideally after 6-9 months you can guage it's effectiveness properly but you will still probably need a good NSAID to help out. The dizziness upon standing may be postural hypotension. The brain is not getting enough oxygen because the body is not appropriately shuttling blood up there and gravity pulls it to your toes. Those with adrenal insufficiency have this, and increasing salt load or if that doesn't work, taking medication for it helps. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form.