Reduction of cardiovascular mortality and morbidity in patients with a history of myocardial infarction or unstable angina pectoris and with either normal or increased cholesterol levels, as an adjunct to correction of other risk factors (see section 5.1). Prior to initiating Pravastatin Tablets, secondary causes of hypercholesterolaemia should be excluded and patients should be placed on a standard lipid-lowering diet, which should be continued during treatment. Hypercholesterolaemia: The recommended dose range is 10 - 40 mg once daily. The therapeutic response is seen within a week and the full effect of a given dose occurs within four weeks, therefore periodic lipid determinations should be performed and the dosage adjusted accordingly. Dosage after transplantation: Following organ transplantation a starting dose of 20 mg per day is recommended in patients receiving immunosuppressive therapy (see section 4.5). Depending on the response of the lipid parameters, the dose may be adjusted up to 40 mg under close medical supervision (see section 4.5). Children and adolescents (8-18 years of age) with heterozygous familial hypercholesterolaemia: The recommended dose range is 10 20 mg once daily between 8 and 13 years of age as doses greater than 20 mg have not been studied in this population and 10- 40 mg daily between 14 and 18 years of age (for children and adolescent females of child bearing potential see section 4.6; for results of the study see section 5.1). Renal or hepatic impairment: A starting dose of 10 mg a day is recommended in patients with moderate or severe renal impairment or significant hepatic impairment. ) : Juego que se practica con un bate y una pelota entre 2 equipos de 9 jugadores, en un campo limitado por 4 almohadillas que marcan la carrera del jugador. Beef steak (Bistec) : loncha de carne, asada o frita. 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