It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Retinal chloroquine retinopathy Plaquenil elevated liver enzymes Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar Drugs - Skip to full site navigation Although there are few drug interactions with hydroxychloroquine, to be safe be sure to tell your doctor about all of the medications you are taking, including over-the-counter drugs and natural remedies. Be sure to notify your other physicians when taking this drug. Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine Aralen and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Malarial parasites invade human red blood cells. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Natural medicine comparable to hydroxychloroquine Is there a drug that I can take to replace plaquenil?, Hydroxychloroquine Plaquenil Can plaquenil cause low white blood countPlaquenil appetite loss Plaquenil hydroxychloroquine Prescription only. 93% of people say it’s worth it. 1 dosage forms. $25.54 is the lowest price near you. Plaquenil hydroxychloroquine Alternatives & Similar Drugs.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine tablets - Cleveland Clinic. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydroxychloroquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Hydroxychloroquine is used to prevent and treat acute attacks of malaria and to treat both acute and chronic rheumatoid arthritis and lupus. It is in a class of drugs known as antimalarials.