However, it can interact with some common medications, altering their effects on your body. If you're curious about the grapefruit warning on many medicines, this article will help you understand why it's there and what your options are. Plaquenil for lupus mechanism Chloroquine acidity Chloroquine phosphate suspension ip Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs. Pinho de Oliveira Ribeiro N1, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC. Medications are processed in your liver and small intestine by a specialized group of proteins called cytochrome P450 (CYPs). Here's a closer look at 32 common drugs that may have dangerous interactions with grapefruit, as well as some alternatives. Plaquenil and antidepressants Medications for Sjogren’s Syndrome NYU Langone Health, Plaquenil Uses, Dosage & Side Effects - Chloroquine lysosome fusionPlaquenil mood swingsHydroxychloroquine 400 mg daily Grapefruit is a delicious citrus fruit with many health benefits. However, it can interact with some common medications, altering their effects on your body. If you're curious about the grapefruit. Grapefruit Warning Can Interact With Common Medications. Anxiety, depression and suicidal ideation in patients with.. QTc Prolongation With Antidepressants and Antipsychotics. Anyone taking an antidepressant should be watched closely for worsening depression or unusual behavior. If you or someone you know has suicidal thoughts when taking an antidepressant, immediately contact your doctor or get emergency help. Keep in mind that antidepressants are more likely to reduce suicide risk in the long run by improving mood. Best antidepressant for lupus patients deleted_user 10/14/2011 I have an appt today with my Rheumy and I want to switch to another antidepressant. I have been taking Effexor 37.5 and doesn't seem to work for me and I think it is making me gain even more weight, although that could also be from some of my other meds. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work.