These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Chloroquine diabetes Plaquenil and amoxicillin Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or. Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild rheumatoid arthritis. They are not as powerful as other DMARDs, but they usually cause fewer side effects. In rare cases, Plaquenil can adversely affect the eyes, and people taking this medicine should be seen by an ophthalmologist at least once a year. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil 200mg side effects Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, What are the side effects of using hydroxychloroquine. Plaquenil liver failurePlaquenil tab 200mg costHydroxychloroquine and nerve damagePlaquenil for chilblainsChloroquine does not inhibit dna synthesis When cut, too much of the drug can be released at once and cause a reaction or side effects. When prescribed 300 mg. daily, you should alternate one tablet one day with two the next. I've been on Plaquenil for almost four years now and it's helped me a lot. Plaquenil side effects - Scleroderma - Inspire. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. What are the side effects of hydroxychloroquine Plaquenil? Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea. These usually get better after the person adjusts to the medication. Malaria. PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported.