Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil retina toxicity Lupus flare while on plaquenil Will plaquenil protet against shingles Retinal damage. Plaquenil may cause irreversible damage to the retina the back of the eye where vision is created. You are required to have an eye exam before taking Plaquenil, then a follow-up as often as needed while taking Plaquenil. Tell your healthcare provider right away if you have some or all of the following symptoms. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food. They are often used in people who no longer respond to methotrexate. Tofacitinib comes as a pill taken twice a day, while baricitinib or upadacitinib are taken once a day with or without food. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). How often do you take plaquenil Are you taking hydroxychloroquine Plaquenil? How often., Hydroxychloroquine Plaquenil Urinary side effects of hydroxychloroquineChloroquine phosphate buy online usaChloroquine transfectionPlaquenil and light sensitivityChloroquine malaria life cycle treatment If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. DMARDs for Treating Rheumatoid Arthritis. Eye screening for patients taking hydroxychloroquine Plaquenil. Aug 26, 2016 I have been taking plaquenil for about 15 years now, I was told by my ophthalmologist that once every two years was sufficient for the 200mg dose twice a day. I have been very lazy, because it is going on three years, so I guest I should make an appointment. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. Newer techniques for evaluation of retinal disease have been developed and these techniques can detect retinal toxicity earlier. My question is for those that have taken Plaquenil/Hydroxychloroquine. How long did it take for it to remove symptoms in your personal experience? I know I've read it can take up to 6 months but what I'm wondering is, do you just wake up one day and find it's kicked in 6 months down the road or more likely, it starts to work slowly over 6 months?