Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine and proguanil dose Cardiomyopathy caused by plaquenil Hydroxychloroquine & cholesterol-lowering medication Side effects plaquenil forums The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy. Suppression 5 mg/kg calculated as base orally on exactly the same day each week; the dose should not exceed 400 mg regardless of weight Comments-Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 10 mg/kg calculated as base may be taken in 2 divided doses 6 hours apart. Mg 5 mg base/kg/dose Max 400 mg 310 mg base/dose PO weekly on the same day of each week, starting 1 to 2 weeks before entering the endemic area and continuing for 4 weeks after leaving the area. Guidelines suggest hydroxychloroquine as an alternative to chloroquine. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil dosage mg kg Plaquenil Risk Calculators, Hydroxychloroquine Dosage Guide with Precautions - Hydroxychloroquine in type 2 diabetes The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. The biggest difference between the 2011 and current recommendations is the need for patients to be dosed by their real. Despite Plaquenil dosing recommendations, retinal toxicity.. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Feb 19, 2020 Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. These guidelines were established to minimize the likelihood of permanent vision loss related to hydroxychloroquine retinopathy. Weight based dosage in adults and pediatric patients 13 mg/kg 10 mg/kg base, not to exceed 800 mg 620 mg base followed by 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, at 6 hours, 24 hours and 48 hours after the initial dose. Plaquenil film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg.