It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Is there a drug interaction between ibuprofen and plaquenil Can erythromycin interact with plaquenil Plaquenil for discoid lupus Chloroquine lupus treatment Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine sulfate 200 mg is equivalent to 155 mg hydroxychloroquine base. Malaria Chemoprophylaxis Infants, Children, and Adolescents Oral 6.5 mg/kg hydroxychloroquine sulfate once weekly on the same day each week; maximum dose 400 mg/dose hydroxychloroquine sulfate; begin 1 to 2 weeks before exposure; continue for at least 4 weeks after leaving endemic area CDC 2016. Hydroxychloroquine increases the QT interval and should not be administered with other drugs known to prolong the QT interval. Ventricular arrhythmias and torsade de pointes TdP have been reported with the use of hydroxychloroquine. Amiodarone, a Class III antiarrhythmic agent, is associated with a well-established risk of QT prolongation and TdP. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine sulfate drug classification HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE, Hydroxychloroquine Professional Patient Advice - Chloroquine phosphate injectionPlaquenil lupus reviewsHow does hydroxychloroquine treat lupusIs hydroxychloroquine safe from dr reddy's lab Contains Nonbinding Recommendations. Draft Guidance on. Hydroxychloroquine Sulfate. This draft guidance, once finalized, will represent the Food and Drug Administration's FDA's Contains Nonbinding Recommendations - Food and Drug.. Plaquenil hydroxychloroquine sulfate dose, indications.. Who should not take Hydroxychloroquine SULFATE? - WebMD. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine Sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites Plasmodium vivax, ovale, and malariae by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.