According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. Kikuchi-fujimoto disease hydroxychloroquine as a treatment Plaquenil and alcohol side effects Can plaquenil treat psoriasis Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Democratic Republic of the Congo Congo-Kinshasa All Chloroquine P. falciparum 90%, P. ovale 5%, P. vivax rare CDC has no limits on the use of chloroquine for the prevention of malaria. Medicines for the Prevention of Malaria While Traveling Chloroquine Aralen™ What is chloroquine? Chloroquine also known as chloroquine phosphate. malaria transmission occurs and which malaria. drugs that are recommended for use in each place. ood choice for longer trips because G. These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine). Chloroquine resistant malaria drug of choice Chloroquine - Wikipedia, Medicines for the Prevention of Malaria While Traveling - Chloroquine. Chloroquine familyChloroquine endosomeChloroquine treatment for cellsPlaquenil causing low wbc count Traditionally, chloroquine has been the first line drug of choice for uncomplicated, non-resistant malaria. However, several types of malaria, and most notably Plasmodium falciparum, the most severe and deadly kind, has become resistant to chloroquine in many places. Drugs for Malaria –. Medicines for the Prevention of Malaria While Traveling.. Chloroquine Dosage Guide with Precautions -. Recognition of the value of chloroquine was delayed, and it was not brought forward until it was reevaluated in the United States and designated the drug of choice against malaria near the end of World War II. Chloroquine quickly proved to be one of the most successful and important drugs ever deployed against an infectious disease. In addition, any of the regimens listed above for the treatment of chloroquine-resistant malaria may be used for the treatment of P. malariae and P. knowlesi infections. P. vivax and P. ovale Chloroquine or hydroxychloroquine remains an effective choice for all P. vivax and P. ovale infections except for P. vivax infections acquired in Papua New Guinea or Indonesia. Treatment of P. vivax infections. P. vivax infections should be treated with an ACT or chloroquine in areas without chloroquine-resistant P. vivax. In areas where chloroquine-resistant P. vivax has been identified, infections should be treated with an ACT, preferably one in which the partner medicine has a long half-life.