Plaquenil induced retinal toxicity

Discussion in 'Northwest Pharmacy' started by dent-help, 21-Feb-2020.

  1. glinjanumax XenForo Moderator

    Plaquenil induced retinal toxicity


    The toxicities can be grouped into categories such as pigmentary retinopathies, crystalline retinopathies, retinal vasculopathies, and retinopathies characterized by retinal edema or folds. Here we present a case of topiramate (Topamax, Ortho-Mc Neil Neurologics) causing transient angle closure and retinal folds.

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    Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Cessation of plaquenil is the standard-of-care treatment for plaquenil-induced toxic maculopathy. If the patient has Possible Early Toxicity Cessation of plaquenil if possible or follow-up at 3 to 6 month intervals until there is further evidence to rule out toxicity; If the patient has Probable Toxicity A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment. Rajen Tailor, * Ibrahim Elaraoud, Peter Good, Monique Hope-Ross, and Robert A. H. Scott

    A 26-year-old woman reported to the emergency room with a chief complaint of sudden, painless loss of vision in both eyes. We follow with a review of the literature regarding topiramate toxicity, as well as a brief review of the other major categories of pharmacologic retinal toxicity.

    Plaquenil induced retinal toxicity

    Retinal toxicity associated with chronic exposure to., H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS

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  6. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by.

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    Hydroxychloroquine is commonly used for the treatment of systemic lupus erythematosus, rheumatoid arthritis, and other inflammatory and dermatologic diseases. Despite its common use, retinal toxicity from hydroxychloroquine has a low incidence 1. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Abstract Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.

     
  7. Ksu-xa Moderator

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil and pregnancy Hi there! I. - Hughes Syndrome Safety of hydroxychloroquine in pregnant patients with. Plaquenil and Pregnancy - Antibiotics Home Page
     
  8. meat User

    PDF Unusual Fundus Autofluorescence Appearance in a. Unusual Fundus Autofluorescence Appearance in a Patient with Hydroxychloroquine Retinal OCT of the right top and left eye bottom showing outer retina and retinal pigment epithelium changes and foveal thinning.

    The Nuts and Bolts of Fundus Autofluorescence Imaging.