The importance of this topic is highlighted by a study identifying potential drug–drug interactions with travel-related medications in 45% of travelers using chronic medications, and 3.5% of interactions are potentially serious. Interactions of commonly used travel-related vaccines and medications are discussed here. Plaquenil gum sores purple Hydroxychloroquine and sulfasalazine Rheumatoid factor plaquenil Malaria tablets chloroquine and proguanil side effects Azithromycin is predicted to increase the exposure to colchicine. Manufacturer advises avoid P-glycoprotein inhibitors or adjust colchicine dose. Severity of interaction Drug Interactions. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Jan 05, 2011 Can I Take Benadryl With Azithromycin. The Drug Interaction CheckerThere are factors to be considered in addition to possible interactions between these medications. However, the spacing between the administration of some vaccines that are not given at the same time needs consideration. Concomitant administration of multiple vaccines, including live attenuated vaccines, generally is safe and effective. Chloroquine and azithromycin interaction Azithromycin Interaction with other Drugs, Azithromycin Oral Route Before Using - Mayo Clinic Hydroxychloroquine atiPlaquenil hand oa Drugs & Medications Chloroquine Phosphate Azithromycin/QT Prolonging Agents Interactions This information is generalized and not intended as specific medical advice. Consult your healthcare. Interactions between Chloroquine Oral and qt-prolonging.. Can I Take Benadryl With Azithromycin - HealthCentral. Lack of a pharmacokinetic interaction between azithromycin.. Zithromax Azithromycin may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. although the prothrombin time was not affected in the dedicated drug interaction study with azithromycin and warfarin. In comparison to chloroquine. Azithromycin, an azalide analog of erythromycin was assayed for its in vitro activity against multidrug-resistant Plasmodium falciparum K1 strain by measuring the 3 H-hypoxanthine incorporation. Azithromycin caused inhibitory effects on the parasite growth with IC 50 and IC 90 values of 8.4 ± 1.2 μM and 26.0 ± 0.9 μM, respectively. Adults with fever, a positive peripheral blood smear, and a positive rapid diagnostic test for Plasmodium falciparum were randomised in both studies to either azithromycin AZ 1,000 mg plus chloroquine CQ 600-mg base AZCQ 1,000 mg once daily for three days or mefloquine hydrochloride MQ 1,250 mg split dose.