Xenical and diabetes

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  1. green man Guest

    Xenical and diabetes


    The result of this inhibition is that about 30% of the daily ingested fat intake is not absorbed. This would lead to a 200-calorie deficit per day in an individual who consumed a diet of 2000 calories/day with 30% of calories as fat. The most common side effects of are gastrointestinal, such as fatty or oily stools, more frequent defecation, and fecal incontinence. Another side effect is a slight reduction in fat-soluble vitamins, generally not outside the reference range. binds to lipases in the gastrointestinal tract and thereby blocks the digestion of dietary triglyc­erides. This inhibition of fat digestion reduces micelle formation and, consequently, the absorption of long-chain fatty acids, cholesterol, and certain fat-soluble vitamins. The degree of fat malabsorption is directly related in a curvilinear fashion to the dose of lost at least 5% or at least 10% of their initial body weight, compared with those randomized to placebo. Prozac and Sarafem, known generically as fluoxetine, are most commonly prescribed as antidepressants. Centers for Disease Control and Prevention and colleagues, patients taking fluoxetine had lost an average of 11 pounds (5.1 kilograms) 24 to 26 weeks after starting the therapy. Xenical, the brand name for orlistat, blocks fat digestion in the intestines. Patients taking orlistat had lost an average of four and a half pounds (two kilograms) 12 to 57 weeks later, and those taking sibutramine had lost an average of 11 pounds 12 to 52 weeks later. Meridia, known generically as subtramine, is an appetite suppressant that works in the brain. “The magnitude of weight loss is modest, however, and the long-term health benefits remain unclear,” the review concludes. Side effects of the therapies included oily bowel movements for those taking orlistat; sweating, tremors and drowsiness among fluoxetine users; and heart palpitations in some sibutramine patients. Although the researchers acknowledge that long-term weight loss is “of paramount importance,” they say their review could help determine how weight loss drugs should fit into the overall picture of type 2 diabetes care. “For example, if weight loss can be demonstrated with drugs in the short term, pharmacotherapy may be combined with behavioral interventions for long-term weight control,” Norris says. The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research.

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    Objective To present an overview and analysis of the previously published XENDOS Xenical in the Prevention of Diabetes in Obese Subjects study. Methods. Xenical did not reduce the risk for the development of diabetes in patients with normal glucose tolerance at baseline. The effect of Xenical to delay the onset of type 2 diabetes in obese patients with IGT is presumably due to weight loss, and not to any independent effects of the drug on glucose or insulin metabolism. The Xenical programmes are based on this principal, and have proved to increase weight loss, increase compliance and increase patient satisfaction," Paul Brown, Global Director Xenical, at Roche Pharmaceuticals said.

    XENICAL is a prescription medicine used with a low calorie diet to increase weight loss in people with obesity. XENICAL may help obese people lose weight and keep the weight off. XENICAL is intended for patients with a BMI of greater than or equal to 30 kg/m2 or a BMI of greater than or equal to 27 kg/m2 in the presence of other risk factors such as hypertension, diabetes, or high cholesterol. It is not known if XENICAL is safe and effective in children under 12 years old. XENICAL should not be used by patients who are pregnant, patients who have food absorption problems, patients who have gallbladder problems, patients who are allergic to orlistat or any of the ingredients in XENICAL *Oily discharge may be clear or have an orange or brown color. These are not all the possible side effects of XENICAL. For more information, patients should ask their doctor or pharmacist. Have systematically reviewed the effectiveness and safety of approved anti-obesity medications in clinical trials that lasted for ⩾1 year for which the results were available by the end of 2002. Norris also report the limited data describing the effects of fluoxetine. More research is needed before the clinical usefulness of this agent can be established. The authors of both reviews conclude that available licensed therapies (eg, sibutramine and orlistat) help induce weight loss. Although of shorter duration, trials of sibutramine suggest that the magnitude of weight reduction is similar to that seen with orlistat. A number of important questions need to be addressed before advocating widespread use of pharmacological treatments for weight reduction. Norris attempted to obtain results of unpublished studies of weight loss treatments but were unable to identify whether publication bias had occurred.

    Xenical and diabetes

    Diabetes Drug May Spur Weight Loss in Obese Nondiabetics, Xenical - FDA prescribing information, side effects and uses

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  5. XENICAL may help obese people lose weight and keep the weight off. XENICAL is intended for patients with a BMI of greater than or equal to 30 kg/m2 or a BMI of greater than or equal to 27 kg/m2 in the presence of other risk factors such as hypertension, diabetes, or high cholesterol.

    • XENICAL.
    • Xenical and Weight Loss The Diabetic News.
    • Xenical And Type 2 Diabetes - diabetestreatment..

    Orlistat Xenical is a lipase inhibitor that prevents the absorption of dietary fat, and it. In the study on the use of Xenical in the Prevention of Diabetes in Obese. Sept. 12, 2001 -- One of the newcomers to the world of weight loss not only helps shed pounds, but also can help overweight people with diabetes drop their. Obesity is associated with dyslipidemia, Type 2 diabetes and an increased risk of cardiovascular. Orlistat has been shown to be an effective adjunct to diet and.

     
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