Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil drusen deposits Interaction with lexapro and plaquenil Fertility Animal studies showed an impairment of male fertility with chloroquine treatment see TOXICOLOGY, Reproductive and development toxicity. There are no data in humans. Special Populations Pregnancy Hydroxychloroquine crosses the placenta. Data are limited regarding the use of PLAQUENIL during pregnancy. Hydroxychloroquine can aggravate pre-existing psoriasis. Does hydroxychloroquine affect fertility or pregnancy? Hydroxychloroquine must be avoided during pregnancy as it may harm the unborn child. If you are planning a family, or wish to breast feed, you should seek advice from your doctor. There is limited evidence relating to the impact of disease modifying anti-rheumatic drugs DMARDs upon male fertility and peri-conception paternal exposure in men with rheumatic disease. Therefore, we conducted a systematic review of available evidence to update information on this subject and guide paternal counselling. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine male fertility Can plaquenil hydroxychloroquine cause infertility., Hydroxychloroquine Skin Support Does hydroxychloroquine cause loss of taste in mouthIs hydroxychloroquine immunosuppressantChloroquine and doxycycline Oct 21, 2015 Its consequences on fertility and pregnancy are not known. Natalizumab alters fertility in female, but not male, animals. No teratogenic effects have been observed in women but the effects are not fully known yet 88, 89. The discontinuation of treatment is recommended 2 months before conception in men. Immunosuppressive drugs and fertility. Safety of anti-rheumatic drugs in men trying to conceive A.. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine is contraindicated during lactation see section 4.3. Fertility. There is no information available on the effect Hydroxychloroquine sulfate on human fertility. In animal studies, chloroquine, a substance related to hydroxychloroquine, showed adverse effects on male fertility see section 5.3. Contraception Which of these prescribed drugs affect male fertility? Asked by Antoine Burkush Updated 10 October 2012 Topics cozaar, nizoral, pentasa, plaquenil, ketoconazole, methotrexate, fertility, male In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk.