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  4. InterMaster New Member

    Postmenopausal women with advanced breast cancer randomized to anastrazole as first-line therapy experienced an increase in time to progression and a more favorable side effect profile compared to women randomized to tamoxifen treatment. Original Date of Publication: November 2000 Postmenopausal breast cancer is classically a hormone-responsive disease whereby the majority of tumors require estrogen stimulation to grow. Tamoxifen is a selective estrogen receptor modulator (SERM) that antagonizes estrogen receptors in the breast and uterus and acts as an agonist, or activator, of estrogen receptors in bone. In the treatment of postmenopausal breast cancer, chemotherapy and endocrine treatment in the form of tamoxifen therapy has been shown to be beneficial. While tamoxifen has been demonstrated to prolong survival and reduce incidence of contralateral breast tumors, its use is also associated with a 2-3 fold increased risk of developing endometrial cancer. Further, while tamoxifen is an estrogen receptor antagonist in the breast, it can also act as a partial agonist such that it may not maximally suppress the effects of estrogen. In the late 1990s, researchers hypothesized that aromatase inhibitors, which inhibit aromatase and thus block the conversion of androgens to estrogens in the peripheral adipose, might allow for more complete estrogen suppression. Tamoxifen for Breast Cancer Treatment - Side Effects Susan G. The NSABP Study of Tamoxifen and Raloxifene STAR trial Low-Dose Tamoxifen Was Safe and Effective at Reducing.
     
  5. TERN New Member

    Now that’s a natural question, considering the vast variety of treatments and medications that were not originally meant to treat anxiety but have, nevertheless, proved to be beneficial as anxiety treatment. Anxiety, as we all know, can be a troublesome condition with several painful physiological and psychological effects. Different medications and treatments work in different ways to control all or some of the symptoms of anxiety. Whether, and to what extent beta blockers like Propranolol can help address the problem of anxiety is still a matter of debate. The use of Propranolol as an anxiety reliever has been accepted by medical practitioners and even the U. Food and Drug Administration (FDA), which approved Inderal in 1967. The FDA has also approved a long-acting form of Propranolol for a single dose a day. But before you decide to turn to Propranolol as an anxiety reliever, you need to understand what a beta blocker really is and how it works. Propranolol in the treatment of anxiety. Propranolol for anxiety? - Anxiety - MedHelp I take Propranolol for anxiety Rachel's story - Headmeds
     
  6. s-47 New Member

    Metformin and Vitamin B12 Deficiency NIDDK Jill Crandall, MD, Professor of Medicine at Albert Einstein College of Medicine in New York, shares insights about metformin and vitamin B12. Thank you, Dr. Crandall, for sharing your expertise. To learn more about metformin and diabetes, check out blog posts from other experts in the series. David.

    Metformin Side Effects, Dosage & Uses -
     
  7. Venom_w Well-Known Member

    Metformin Side Effects, Dosage, Uses, and More Metformin oral tablet is a prescription drug that’s used along with diet and exercise to treat high blood sugar levels caused by type 2 diabetes. Tablets are available as generic drugs and as.

    Long-Term Metformin Treatment Found to Reduce Risk of Heart.