No matter what kind of medicine you take, whether OTC (over-the-counter) or prescription, it is destined to take a trip through your kidneys. Taking a drug the wrong way or in excessive amounts can damage these vital, bean-shaped organs and lead to serious complications. In the worst-case scenario, it could necessitate a kidney transplant.“Compared with 30 years ago, patients today…have a higher incidence of diabetes and cardiovascular disease, take multiple medications, and are exposed to more diagnostic and therapeutic procedures with the potential to harm kidney function,” according to Cynthia A. Naughton, Pharm D, senior associate dean and associate professor in the department of pharmacy practice at North Dakota State University. All of these factors are associated with an elevated risk of kidney damage. An estimated 20% of cases of acute kidney failure are due to medications. The technical term for this scenario is “nephrotoxicity,” which is growing more common as the aging population grows, along with rates of various diseases. viagra recommended dose A dosage of 1 g of valacyclovir 3 times per day (TID) for 7 days has already been shown to be superior to an oral dosage of 800 mg acyclovir 5 times per day for 7 days in immunocompetent individuals. The objective of this study was to assess the safety and efficacy of an oral dosage of valacyclovir, 1 g TID versus 2 g TID, for the treatment of herpes zoster in immunocompromised patients ⩾18 years of age. The oral dosage schedule of 2 g of valacyclovir TID reaches acyclovir plasma levels similar to those achieved with intravenous acyclovir therapy given to immunocompromised patients (10 mg/kg every 8 h for 7 days). In this double-blind study, 87 immunocompromised patients with clinical evidence of localized herpes zoster were randomized to receive oral valacyclovir therapy for 7 days, either 1 g TID or 2 g TID, within 72 h after onset of zoster rash. Patients were seen and assessed for cutaneous healing, zoster-associated pain (ZAP), and/or zoster-associated abnormal sensations (ZAAS), up to 24 weeks. Participants in both arms of the study demonstrated similar median times to full crusting of the rash (8 days), and both dosages were safe and effective therapies for reduction of ZAP and ZAAS in the immunocompromised patient population Trials registration Clinical identifier: NCT00006131 Herpes zoster, or shingles, is a common disease caused by a reactivation of the varicella-zoster virus (VZV). Subsequent to primary VZV infection (i.e., chickenpox), the virus lies latent in the dorsal root ganglia, and reactivation can occur at any age [1, 2]. 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It is usually taken every 8 hours (three times a day) for 7 days to treat shingles. To treat genital herpes it is usually taken twice a day for 5 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Use this medication as soon as possible after symptoms appear. Continue to take valacyclovir even if you feel well. Please complete all the fields below to send the bad drug report. Each field is required to be completed in order to send. The submission of this form does not form an attorney client relationship. An attorney client relationship will only be formed after the execution and return of a retainer agreement. Valtrex may decrease kidney function, especially when combined with other drugs. When used along with other kidney damaging medications, Valtrex can be extremely dangerous. The following may be harmful to the kidneys: Valtrex is an FDA pregnancy Category B drug. Does valtrex cause constipation MSU @michiganstateu Twitter, Valtrex - Uses, Side Effects, Interactions - Buy turkish viagra Valtrex does not prevent the spread of herpes, so take precautions to protect. Although rare, Valtrex can cause a life-threatening disorder that. Valtrex Valacyclovir - Side Effects, Dosage, Interactions - Drugs Valtrex Side Effects and Contraindications - Just Herpes Common Side Effects of Valtrex Valacyclovir Hydrochloride Drug. Since October 2013 I have had 5 episodes of shingles. The 1st 2 times were treated with 3000mg valtrex and steroid for 7 days.within 5. doxycycline mrsa Find information about common, infrequent and rare side effects of Valtrex Oral. Constipation; Diarrhea; Disorder Of The Digestive System; Dizzy; Joint Pain. Detailed drug Information for Valtrex. Includes common brand names, drug descriptions, warnings, side effects and dosing information.