This medicine is indicated in adults for the local treatment, by intra-articular or periarticular injection, of the following conditions: rheumatoid arthritis; osteoarthritis; synovitis not associated with infection; tennis elbow; golfer's elbow, and bursitis. This medicine is also suitable for administration by the intramuscular route in conditions requiring systemic corticosteroids, e.g. suppression of inflammatory and allergic disorders such as bronchial asthma, anaphylaxis, ulcerative colitis and Crohn's disease. Undesirable effects may be minimised by using the lowest effective dose for the minimum period and by administering the daily requirement as a single morning dose or whenever possible, as a single morning dose on alternate days. Frequent patient review is required to titrate the dose against disease activity. Paediatric Population This medicine is not suitable for use in children. Elderly Steroids should be used cautiously in the elderly since adverse effects are enhanced by old age (see section 4.4). clonidine wikipedia Corticosteroid drugs — including cortisone, hydrocortisone and prednisone — are useful in treating many conditions, such as rashes, lupus and asthma. But these drugs also carry a risk of serious side effects. Working with your doctor, you can take steps to reduce these side effects so that the benefits of corticosteroid treatment outweigh the risks. Corticosteroids mimic the effects of hormones your body produces naturally in your adrenal glands, which are small glands that sit on top of your kidneys. When prescribed in doses that exceed your body's usual levels, corticosteroids suppress inflammation. This can reduce the signs and symptoms of inflammatory conditions, such as arthritis and asthma. Corticosteroid drugs are used to treat rheumatoid arthritis, lupus, asthma, allergies and many other conditions. 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